- Highest sensitivity and specificity, 100- to 1000-fold improved
- Performed on cfDNA obtained from a simple blood sample
- Rapid turn-around time (1 day sample to result)
Detect, quantify, and monitor EGFR T790M mutations in blood with unparalleled sensitivity.
The SAGAsafe® EGFR T790M assay (CE-IVD) achieves industry-leading superior performance by employing the patented ultrasensitive SAGAsafe® digital PCR technology which in comparison to traditional approaches enhances true-positive signals and at the same time reduces false-positive signals. This leads to a 100- to 1000-fold improvement in detection limit compared to competitor technologies and kits.
SAGAsafe® EGFR T790M is performed on cfDNA obtained from a simple blood sample which means that patient material is easily available and allows for rapid and low-cost repetition of testing.
|Mutation targeted||EGFR p.T790M (c.2369C>T)|
|System||Validated on the Bio-Rad QXDx™/QX200™ ddPCR™ system|
|Sample type||cfDNA derived from plasma samples|
|Kit sizes available||25 samples or 100 samples|
Limit of Blank (LoB) and Limit of Detection (LoD) at maximum loading and with 95% confidence interval
|95% CI||Limit of Blank||Limit of Detection|
|SAGAsafe® EGFR T790M test||0.0010% MAF||0.0037% MAF|
This product is not commercially available in all countries.